Carboxylated 70 nm Green Fluorescent Nanodiamond in DI water

Carboxylated 70 nm Green Fluorescent Nanodiamond in DI water

Catalog Number:
N002336388ADÁ
Mfr. No.:
NDNVN70nmMd10ml
Price:
$794
  • Size:
    10 mL (1 mg/mL)
    Quantity:
    Add to Cart:
      • Overview
        • Green FND is produced from natural diamond. While fluorescence derives from a majority of green-emitting NVN centers, trace amounts of red-emitting NV centers also coexist.

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          Background

          Nanodiamonds (NDs) have been successfully applied in different materials science fields due to their stiffness, lubricity, mechanical resistance, and refractivity. Moreover, due to their high biocompatibility, inherent inertness, ability to easily penetrate cell membranes, and well-established surface chemistry, NDs are explored as a powerful carrier for delivering different drugs within target cells and monitoring intracellular processes.
          The bioconjugation of NDs to specific biomolecules such as peptides, proteins, nucleic acids, and other bioactive molecules can be classified as noncovalent, covalent, and interlayer mediated approaches based on the interactions between NDs and these biomolecules. NDs are able to form complexes with proteins or lipophilic drugs through hydrophobic interactions, while the surface charge of NDs enables the loading of the biomolecules through electrostatic attraction. Since the non-covalent bond interaction is weak and non-specific, biomolecules could gradually detach from the ND surface under biological conditions. For NDs with functional groups such as hydroxyl and carboxyl groups, it is possible to conjugate to biomolecules through covalent bonds, such as ester and amide bonds, thus providing a stronger and more stable connection. To enable practical applications of functionalized NDs in physiological environments, interlayers consisting of hydrophilic polymers are introduced between NDs and bioactive substances to enhance their aqueous dispersibility and provide more functionalities for chemical binding. PEG chains terminated with functional groups such as amino, thiol and azido groups are often employed to selectively bind a range of biomolecules through covalent bonds.

          More Details

      • Properties
        • Categories
          Carboxylated Green Fluorescent Nanodiamond
          Particle Size
          70-80 nm

          * By purchasing this material, recipient agrees that the Material is to be used solely for testing purpose, and the Material will not be used in human subjects, in clinical trials, or for diagnostic purposes involving human subjects without the written consent of the Provider.

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