Canine Alpha 1-Antitrypsin ELISA

The Canine Alpha 1-Antitrypsin ELISA is a highly sensitive two-site enzyme linked immunoassay (ELISA) for measuring A1AT in biological fluid of dogs. A1AT is a 52 kDA serine protease inhibitor (serpin) in blood, which protects tissue from enzymes from inflammatory cells, especially elastase. In certain acute phase inflammatory reactions, A1AT is elevated in order to limit the damage caused by activated neutrophil granulocytes and their enzyme elastase. Disorders of A1AT include A1AT deficiency, a hereditary disorder that can lead to severe tissue breakdown during inflammation. This may result in pulmonary emphysema and liver cirrhosis, in severe cases. Genetic variants of A1AT do occur.
The Canine Alpha 1-Antitrypsin ELISA is for Research Use Only.

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