Calcium Sensing Receptor - ExpressMAX™ Human GPCR ORF Clones

Calcium Sensing Receptor - ExpressMAX™ Human GPCR ORF Clones

Catalog Number:
MEV1268644CAN
Mfr. No.:
G0515-B; G0515-Plus
Price:
$575
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      • Overview
        • Calcium Sensing Receptor is a GPCR that is expressed in the parathyroid gland and the cells lining the kidney tubule. In the parathyroid gland, CaSR controls calcium homeostasis by regulating the release of parathyroid hormone (PTH). Decreased calcium binding on the extracellular side gives a conformation change in the receptor, which initiates the phospholipase C pathway, presumably through a Gqα type of G protein.

          Includes:
          ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
          – Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
          Mammalian Transfection Kits (Cat. No. – PLUS)
          – 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
          – 0. 2 mL CANFAST™ Transfection Reagent.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Human GPCR ORF Clones
          Other Properties
          Plasmid size: 8573 bp
          Promoter: pMLV
          ORF Sequence (GenBank based): NM_000388
          Protein Sequence (SwissProt): P41180
          Bacterial Selection Antibiotics: Ampicillin
          Mammalian Selection Antibiotic: Neomycin
          Alternative names: CaSR, CAR
          Storage
          ExpressMAX™ GPCR ORF Clones (-20 °C) and CANFAST™ (4 °C).

          * This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals.

      • Applications
        • Application Description
          Functional assays, as protein immobilization, cellular localization and other functional assays.
          High-throughput and large scale protein production and purification.
          Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

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