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Overview
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Calculated MW: 138kDa/240kDa/249kDa/250kDa/254kDa
Observed MW: 254kDaPlease contact us at for specific academic pricing.
Background
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
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