C1QTNF3 Recombinant Protein

C1QTNF3 Recombinant Protein

Catalog Number:
P001416124ABE
Mfr. No.:
Abe32-3376
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • C1QTNF3 Human Recombinant produced in E. Coli is a single, non-glycosylated, Polypeptide chain containing 234 amino acids and having a molecular mass of 25.4 kDa. The protein contains an extra 10 aa His tag at N-terminus. The C1QTNF3 amino acid sequence is identical to UniProtKB/Swiss-Prot entry Q9BXJ4 amino acids 23-246. The C1QTNF3 is purified by proprietary chromatographic techniques. C1QTNF3 also called Cartducin is a novel angiogenic factor in the formation of neointima following angioplasty. C1QTNF3 a paralog of Acrp30 (adiponectin). C1QTNF3 is a secretory protein produced by chondrogenic precursors & proliferating chondrocytes, and belongs to a novel C1q family of proteins. Cartducin promotes the growth of mesenchymal chondroprogenitor cells & chondrosarcoma-derived chondrocytic cells in vitro. Cartducin stimulates mesenchymal chondroprogenitor cell proliferation through extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways. C1QTNF3 promotes proliferation & the migration of endothelial cells.

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      • Properties
        • Protein Name
          Complement C1q tumor necrosis factor-related protein 3, Secretory protein CORS26, C1QTNF3, CTRP3, Cors, Corcs, CORS26, FLJ37576, Cartducin.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          The purity of C1QTNF3 is greater than 95% as determined by SDS PAGE.
          Formulation
          Human C1QTNF3 was filtered (0.4µm) and lyophilized in 0.5 mg/ml in 0.05M Acetate buffer pH4.
          Storage
          Store lyophilized C1QTNF3 at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted C1QTNF3 can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

      • Applications
        • Application Description
          It is recommended to add 0.1M Acetate buffer pH4 to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10μg/ml. In higher concentrations the solubility of the protein is limited. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

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