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Overview
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Observed MW: 100KDa
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Background
Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells. Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1. Required for the localization of TEX11 and MSH4 to recombination intermediates.
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