C1GALT1 Recombinant Protein

C1GALT1 Recombinant Protein

Catalog Number:
P001417091ABE
Mfr. No.:
Abe32-2196
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • C1GALT1 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 357 amino acids (30-363 a.a) and having a molecular mass of 41.4kDa. C1GALT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Core 1 Beta3-Gal-T1 also known as, C1GALT1 creates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for lots of extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice have shown that this gene takes a main role in angiogenesis, thrombopoiesis and kidney homeostasis.

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      • Properties
        • Protein Name
          Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-Beta-Galactosyltransferase 1, Core 1 Beta3-Gal-T1, Core 1 O-Glycan T-Synthase, Core 1 UDP-Galactose:N-Acetylgalactosamine-Alpha-R Beta 1, 3 Galactosyltransferase1, B3Gal-T8, EC 2.4.1.122
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 80.0% as determined by SDS-PAGE.
          Formulation
          C1GALT1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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