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Overview
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C1D Human Recombinant produced in E. coli is a single polypeptide chain containing 164 amino acids (1-141) and having a molecular mass of 18.4kDa. C1D is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. C1D s which regulates TRAX/Translin complex formation takes part in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. C1D which activates PRKDC in the presence of linear DNA and supercoiled DNA also induces apoptosis in a p53/TP53 dependent manner.
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Overview