Butyl Bestarose HP - Butyl HIC Resins

Hydrophobic interaction chromatography (HIC) is a chromatographic method that uses the interaction between the hydrophobic groups carried by biological molecules and the hydrophobic ligands on the stationary phase to separate substances. Salt ions can destroy the hydration membrane on the surface of biomolecules and promote the binding between hydrophobic groups and ligands.
The base matrix of Butyl Bestarose HP resin is highly cross-linked agarose, which retains the excellent hydrophilicity and pore structure of natural polysaccharide compounds as well as the good compatibility with biological macromolecules. The average particle size of Butyl Bestarose HP is 34μm, providing a higher resolution than Butyl Bestarose FF. The surface contains hydrophobic Butyl ligands, which is particularly suitable for the polishing of recombinant proteins, antibodies, vaccines, VLP particles and other highly hydrophobic biological molecules.

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