Name: BUB3 Recombinant Protein
Price: Inquiry

- Overview
  - BUB3 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 351 amino acids (1-328 a.a.) and having a molecular mass of 39.5kDa. BUB3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Mitotic checkpoint protein BUB3,( BUB3), is a saved component of the mitotic spindle assembly complex (MCC). The encoded protein has 4 WD repeat domains and has a similar sequence as the yeast BUB3 protein. BUB3 is vital for the kinetochore localization of BUB1 and BUBR1. BUB3 participates in the central spindle checkpoint pathway that operates during early embryogenesis. Furthermore BUB3 has a part in regulating the establishment of correct kinetochore-microtubule attachments.
    
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- Properties
  - Protein Name
    
    BUB3L, hBUB3, Mitotic checkpoint protein BUB3.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 85.0% as determined by SDS-PAGE.
    
    Formulation
    
    BUB3 protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

BUB3 Recombinant Protein

BUB3 Recombinant Protein

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