BSA Creatine L8 Conjugate

Creatine is an amino acid that has an important role in cellular energy metabolism. It is present either as a free form or creatine phosphate in mammalian tissues such as liver, kidneys, muscle, brain, and blood. Creatine has been used to treat or prevent several neuromuscular conditions. Immunoassay can be a great method of detecting creatine. However, creatine is difficult to modify due to its intrinsic characteristics. Since Creatine is a very small molecule it is generally very difficult to generate an antibody that binds strongly to the protein for detection. The BSA-creatine conjugate is designed with a flexible linker of optimal length (8-atom length, L8) and a labeling chemistry that does not interfere with creatine binding. Each lot of the conjugate consists of an optimally loaded BSA with (8-15) creatine molecules per BSA molecule as determined by mass spectrometry.

• Key Features of this BSA Creatinine Conjugate
• Frozen liquid in PBS buffer. Ready to use directly after defrosting.
• Long Flexible linker and non-interfering labeling chemistry for easy access
• Optimal loading with average of 8-15 creatine molecules per BSA for strong binding with low background. See each lot for specific loading.
• Concentration accurately determined by UV/HPLC
• Loading accurately determined by MS

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