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Bis-sulfone NHS Ester

Bis-sulfone NHS Ester

Catalog Number:
PG01492487ALA
Mfr. No.:
B597115-100mg; B597115-500mg; B597115-1g
Price:
$1,010
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      • Overview

        • Bis-sulfone NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact.

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      • Properties
        • CAS Number
          899452-51-8
          Molecular Formula
          C29H27NO9S2
          Molecular Weight
          597.7
          Purity
          95%
          Storage
          Store at -20°C
          Shipping
          Dry ice
          SMILES
          CC1=CC=C(C=C1)S(=O)(=O)CC(CS(=O)(=O)C2=CC=C(C=C2)C)C(=O)C3=CC=C(C=C3)C(=O)ON4C(=O)CCC4=O
          InChi
          InChI=1S/C29H27NO9S2/c1-19-3-11-24(12-4-19)40(35,36)17-23(18-41(37,38)25-13-5-20(2)6-14-25)28(33)21-7-9-22(10-8-21)29(34)39-30-26(31)15-16-27(30)32/h3-14,23H,15-18H2,1-2H3
          InChi Key
          NTRPBIATANVSPI-UHFFFAOYSA-N
          PubChem CID
          6420087
          Others
          IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 4-[3-(4-methylphenyl)sulfonyl-2-[(4-methylphenyl)sulfonylmethyl]propanoyl]benzoate

          * For research use only. Not for use in human or animal.

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