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Overview
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Biapenem is a broad-spectrum carbapenem antibiotic with activity against Gram-positive and Gram-negative bacteria. It is useful for pathogens causing intra-abdominal, lower respiratory, and urinary tract infections. It is highly resistant to most types of β-lactamases from both aerobes and anaerobes. It is a 1-β-methylcarbapenem and has similar antibacterial activity to Imipenem, with less neurotoxicity and increased stability against human renal dehydropeptidase-I. The compound can be used in pharmacokinetic studies.
Biapenem is sparingly soluble in water.Please contact us at for specific academic pricing.
Background
Biapanem has a similar structure and activity to imipenem but has a methyl group in the 1-beta position. Addition of the methyl group confers resistance to human renal dehydropeptidase-I (DHP-1).
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