Beclomethasone dipropionate

- Overview
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    Background
    
    Beclomethasone dipropionate(BDP) is a topically active and anti-inflammatory corticosteroid used in treatment of asthma and rhinitis [1].Beclomethasone dipropionate(BDP) is a topically active and anti-inflammatory corticosteroid used in treatment of asthma and rhinitis. In addition, Beclomethasone dipropionate has been reported to be previously developed as aqueous nasal formulations for the treatment of Allergic rhinitis. Moreover, Beclomethasone dipropionate has shown the availability in dry nasal aerosol formulations as chiorofluoro carbon metered-dose inhaler nasal sprays [1].
    
    [1] Ratner PH1, Melchior A, Dunbar SA, Tantry SK, Dorinsky PM. Pharmacokinetic profile of beclomethasone dipropionate hydrofluoroalkane after intranasal administration versus oral inhalation in healthy subjects: results of a single-dose, randomized, open-label, 3-period crossover study. Clin Ther. 2012 Jun;34(6):1422-31.
- Properties
  - Categories
    
    Corticosteroid used for asthma and rhinitis
    
    Alternative Name
    
    [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
    
    CAS Number
    
    5534-09-8
    
    Molecular Formula
    
    C28H37ClO7
    
    Molecular Weight
    
    521.04
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in H2O; ≥12.72 mg/mL in EtOH with ultrasonic; ≥16.95 mg/mL in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)Cl)O)C)C)OC(=O)CC
    
    * For Research Use Only

Documents

COA (Certificate Of Analysis)

MSDS (Material Safety Data Sheet)

Datasheet

Beclomethasone dipropionate

Background

Documents

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