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Overview
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Calculated MW: 44kDa/48kDa/54kDa/55kDa
Observed MW: 56kDaPlease contact us at for specific academic pricing.
Background
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.
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