BABAM2 Polyclonal Antibody

BABAM2 Polyclonal Antibody

Catalog Number:
A001506126RED
Mfr. No.:
RD211008A
Price:
$253
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      • Overview
        • Calculated MW: 44 kDa
          Gene Accession: BC001251

          Please contact us at for specific academic pricing.

          Background

          Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellular juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1). BRE also binds to the death receptor, FAS. BRE downregulates TNFa-induced activation of NFkB and may play a role in homeostasis or cellular differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medulla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant protein of human BRE
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% sodium azide and 50% glycerol, PH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.5 mg/mL
          Antigen
          6030405P19Rik, AI429776, B830038C02Rik, Brain and reproductive organ expressed (TNFRSF1A modulator), brain and reproductive organ expressed protein, Brain and reproductive organ-expressed protein, BRCA1 A complex subunit BRE, BRCA1-A complex subunit BRE, BRCA1/BRCA2 containing complex subunit 4, BRCA1/BRCA2 containing complex subunit 45, BRCA1/BRCA2-containing complex subunit 45, BRCC4, BRCC45, bre, BRE (UniProt:Q9NXR7)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:50-1:200

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