B-Raf Polyclonal Antibody

B-Raf Polyclonal Antibody

Catalog Number:
A001513944RED
Mfr. No.:
RD89434A
Price:
$416
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      • Overview
        • Calculated MW: 89kDa
          Observed MW: 92KDa

          Please contact us at for specific academic pricing.

          Background

          This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Recombinant fusion protein of human B-Raf
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          BRAF, B-RAF1, B-raf, BRAF1, NS7, RAFB1, serine/threonine-protein kinase B-raf (Gene ID:673; UniProt:P15056)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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