Azido-PEG4-Val-Cit-PAB-OH

Azido-PEG4-Val-Cit-PAB-OH

Catalog Number:
PG01492304ALA
Mfr. No.:
A596152-100mg; A596152-250mg; A596152-500mg; A596152-1g
Price:
$561
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      • Overview
        • Azido-PEG4-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility.

          Please contact us at for specific academic pricing.

      • Properties
        • CAS Number
          2055024-64-9
          Molecular Formula
          C29H48N8O9
          Molecular Weight
          652.8
          Purity
          96%
          Storage
          Store at -20°C
          Shipping
          Dry ice
          SMILES
          CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)NC(=O)CCOCCOCCOCCOCCN=[N+]=[N-]
          InChi
          InChI=1S/C29H48N8O9/c1-21(2)26(36-25(39)9-12-43-14-16-45-18-19-46-17-15-44-13-11-33-37-31)28(41)35-24(4-3-10-32-29(30)42)27(40)34-23-7-5-22(20-38)6-8-23/h5-8,21,24,26,38H,3-4,9-20H2,1-2H3,(H,34,40)(H,35,41)(H,36,39)(H3,30,32,42)/t24-,26-/m0/s1
          InChi Key
          AXRCLOURQJMPLC-AHWVRZQESA-N
          PubChem CID
          119058238
          Others
          IUPAC Name: (2S)-2-[[(2S)-2-[3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanoylamino]-3-methylbutanoyl]amino]-5-(carbamoylamino)-N-[4-(hydroxymethyl)phenyl]pentanamide

          * For research use only. Not for use in human or animal.

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