Azido-PEG4-PFP ester

Azido-PEG4-PFP ester

Catalog Number:
PG01492299ALA
Mfr. No.:
A595037-100mg; A595037-250mg; A595037-1g
Price:
$428
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      • Overview
        • Azido-PEG4-PFP ester is a PEG derivative containing an azide group and a PFP group. The azide group enables Click Chemistry. The PFP ester is a better leaving group compared to a hydroxyl group and can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer adds to the water solubility of this reagent.
          N3-PEG4-C2-Pfp ester is a non-degradable 4-unit PEG linker that can be used to synthesize antiboy-coupled active molecules (ADCs). N3-PEG4-C2-Pfp ester is a click chemical. It contains Azide groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Strain-promoted acetylene-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups.
          Application: Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

          Please contact us at for specific academic pricing.

      • Properties
        • Alternative Name
          N3-PEG4-C2-Pfp ester
          CAS Number
          1353012-00-6
          Molecular Formula
          C17H20F5N3O6
          Molecular Weight
          457.35
          Purity
          95%
          Other Properties
          Solubility: Soluble in DMSO, DCM, DMF
          Sensitivity: Light Sensitive
          Storage
          Protected from light. Store at -20°C
          Shipping
          Dry ice
          SMILES
          C(COCCOCCOCCOCCN=[N+]=[N-])C(=O)OC1=C(C(=C(C(=C1F)F)F)F)F
          InChi
          InChI=1S/C17H20F5N3O6/c18-12-13(19)15(21)17(16(22)14(12)20)31-11(26)1-3-27-5-7-29-9-10-30-8-6-28-4-2-24-25-23/h1-10H2
          InChi Key
          QSIFGTAWLLFXPY-UHFFFAOYSA-N
          PubChem CID
          60146185
          Others
          IUPAC Name: (2,3,4,5,6-pentafluorophenyl) 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanoate

          * For research use only. Not for use in human or animal.

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