Avermectin B1b

- Overview
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    Background
    
    Avermectin B1 is a mixture of avermectins containing >80% avermectin B1a and <20% avermectin B1b. B1a and B1b have very similar biological and toxicological properties.
    In vitro: The avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium. Avermectin B1 is a natural fermentation product of this bacterium.
    In vivo: Avermectin B1 therapy resulted in significant decreases in mean strongyle egg after treatment. All horses given ivermectin or avermectin B1 had zero strongyle egg counts 14 and 28 d after treatment. The oral administration of avermectin B1 appeared to be highly efficacious against intestinal strongyles and Onchocera microfilaria [1].
    Clinical trial: Currently no clinical data are available
    
    [1] Mogg TD, Pollitt CC, Willmore JP, Thompson H. Efficacy of avermectin B1 given orally against equine intestinal strongyles and Onchocera microfilaria. Aust Vet J. 1990;67(11):399-401.
- Properties
  - Categories
    
    mixture of avermectins
    
    CAS Number
    
    65195-56-4
    
    Molecular Formula
    
    C47H70O14
    
    Molecular Weight
    
    859.05
    
    Appearance
    
    A white solid
    
    Purity
    
    98.00%
    
    Solubility
    
    Soluble in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CC([[email protected]](O1)([H])[[email protected]@](C=C[[email protected]@]21C[[email protected]](O3)([H])C[[email protected]@](O2)([H])C/C([H])=C([[email protected]](O[[email protected]@]4([H])C[[email protected]@](OC)([H])[[email protected]](O[[email protected]@]5([H])C[[email protected]@](OC)([H])[[email protected]](O)([H])[[email protected]](O5)([H])C)([H])[[email protected]](O4)([H])C)([H])[[email protected]@](/C([H])=C([H])/C([H])=C([[email protected]@]67O)\CO[[email protected]]7([H])[[email protected]@](O)([H])C(
    
    * For Research Use Only

Documents

COA (Certificate Of Analysis)

MSDS (Material Safety Data Sheet)

Avermectin B1b

Background

Documents

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