Name: ATP6V1C1 Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA
Price: 253.00 USD

Overview
- Calculated MW: 44 kDa
  Observed MW: Refer to figures
  Gene Accession: BC010960
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Fusion protein of human ATP6V1C1
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  0.6 mg/mL
  
  Antigen
  
  ATP6C, ATP6D , ATP6V1C1, ATPase H+ transporting lysosomal (vacuolar proton pump) 42kD, ATPase H+ transporting lysosomal 42kD V1 subunit C isoform 1, ATPase H+ transporting lysosomal 42kDa V1 subunit C isoform 1, ATPase H+ transporting lysosomal 42kDa V1 subunit C1 , ATPase H+ transporting lysosomal V1 subunit C1, FLJ20057, H(+) transporting two sector ATPase subunit C, H+ ATPase C subunit , H+ transporting ATPase chain C vacuolar , Subunit C of vacuolar proton ATPase V1 domain, V ATPase C subunit , V ATPase subunit C 1, V-ATPase subunit C 1, V-type proton ATPase subunit C 1, Vacuolar ATP synthase subunit C, Vacuolar proton pump 42 kD subunit , Vacuolar proton pump C subunit , Vacuolar proton pump subunit C 1, Vacuolar protonATPase subunit C VI domain , VATC, VATC1, VATPase C subunit , VATPase subunit C 1, VMA5 (UniProt:P21283)
  
  * For reference only.

Applications

Application

WB; IHC; ELISA

Application	Dilutions
WB	1:500-1:2000
IHC	1:100-1:200
ELISA	1:5000-1:10000

ATP6V1C1 Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA

ATP6V1C1 Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA

Background

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