ARIH2 Polyclonal Antibody (1.38 mg/mL) for WB, IHC, ELISA

ARIH2 Polyclonal Antibody (1.38 mg/mL) for WB, IHC, ELISA

Catalog Number:
A001507070RED
Mfr. No.:
RD219064A
Price:
$253
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      • Overview
        • Calculated MW: 58 kDa
          Observed MW: Refer to figures
          Gene Accession: BC000422

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          Background

          TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Fusion protein of human ARIH2
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1.38 mg/mL
          Antigen
          HT005, all trans retinoic acid inducible RING finger, Ari 2, Ari-2, ARI2, ARI2, Ariadne 2, Ariadne 2 protein homolog, ariadne homolog 2 (Drosophila), ariadne homolog 2, Ariadne RBR E3 ubiquitin protein ligase 2, ARIH 2, Arih2, E3 ubiquitin protein ligase ARIH2, E3 ubiquitin-protein ligase ARIH2, protein ariadne 2 homolog, Protein ariadne-2 homolog, Triad 1, TRIAD1, Triad1 protein, UIP48 (UniProt:O95376)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:1000-1:5000
          IHC 1:50-1:300
          ELISA 1:5000-1:10000

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