APOA1 Polyclonal Antibody (1 mg/mL) for WB, IHC, IF

APOA1 Polyclonal Antibody (1 mg/mL) for WB, IHC, IF

Catalog Number:
A001508935RED
Mfr. No.:
RD265812A
Price:
$347
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      • Overview
        • Calculated MW: 30 kDa
          Observed MW: 31 kDa

          Please contact us at for specific academic pricing.

          Background

          This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant fusion protein of human APOA1 (NP_000030.1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          APOA1, apo(a) (Gene ID:335; UniProt:P02647)

          * For reference only.

      • Applications
        • Application
          WB; IHC; IF
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:50-1:100
          IF 1:50-1:200

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