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Overview
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Calculated MW: 19kDa/21kDa/73kDa/78kDa/83kDa
Observed MW: 70kDaPlease contact us at for specific academic pricing.
Background
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
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