Anti-Zika virus(ZIKV)(strain Zika SPH2015) ZIKV-E/Envelope protein Monoclonal Antibody (1mg/mL) for ELISA

Anti-Zika virus(ZIKV)(strain Zika SPH2015) ZIKV-E/Envelope protein Monoclonal Antibody (1mg/mL) for ELISA

Catalog Number:
A001514807RED
Mfr. No.:
RD90543A
Price:
$500
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Envelope of Zika virus is resposible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent to those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross reactivity with dengue and YF.Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76% of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          Zika Virus
          Immunogen
          Recombinant ZIKV (strain Zika SPH2015) Envelope protein (Domain III, His Tag)
          Purification
          Protein A purification
          Conjugate
          Unconjugated
          Formulation
          0.2 μm filtered solution in PBS
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          E, Envelope Protein

          * For reference only.

      • Applications
        • Application
          ELISA
        • Application Dilutions
          ELISA 1:1000-1:10000

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