Name: Anti-XRCC5 antibody
Price: 297.00 USD

Overview
- The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 540-732 of human XRCC5 (NP_066964. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  X-Ray Repair Cross-Complementing Protein 5; 86 Kda Subunit Of Ku Antigen; Atp-Dependent Dna Helicase 2 Subunit 2; Atp-Dependent Dna Helicase II 80 Kda Subunit; Ctc Box-Binding Factor 85 Kda Subunit; Ctc85; Ctcbf; Dna Repair Protein Xrcc5; Ku80; Ku86; Lupus Ku Autoantigen Protein P86; Nuclear Factor Iv; Thyroid-Lupus Autoantigen; Tlaa; X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 5; Double-Strand-Break Rejoining (Gene ID:7520; UniProt:P13010)
  
  * For research use only