Anti-WNT5A antibody

Anti-WNT5A antibody

Catalog Number:
A001035327STJ
Mfr. No.:
STJ26117
Price:
$297
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      • Overview
        • The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 101-380 of human Wnt5a (NP_003383. 2).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Protein Wnt-5a (Gene ID:7474; UniProt:P41221)

          * For research use only

      • Applications
        • Application
          IHC
        • Application Dilutions
          IHC 1:50-1:100

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