Anti-V-ATPase H antibody

Anti-V-ATPase H antibody

Catalog Number:
A001051596STJ
Mfr. No.:
STJ96226
Price:
$224
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      • Overview
        • V-ATPase H is a protein encoded by the ATP6V1H gene which is approximately 55, 9 kDa. V-ATPase H is localised to the cytosol. It is involved in insulin receptor recycling and innate immune system. It is a multi-subunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. V-ATPase H is widely expressed. Mutations in the ATP6V1H gene may result in an involvement in the HIV life cycle. STJ96226 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of V-ATPase H protein.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Synthesized peptide derived from human V-ATPase H
          Purification
          The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
          Storage
          Store at -20°C and avoid repeat freeze-thaw cycles.
          Concentration
          1 mg/ml
          Regulatory Status
          RUO
          Antigen
          V-Type Proton Atpase Subunit H; V-Atpase Subunit H; Nef-Binding Protein 1; Nbp1; Protein Vma13 Homolog; V-Atpase 50/57 Kda Subunits; Vacuolar Proton Pump Subunit H; Vacuolar Proton Pump Subunit Sfd (Gene ID:51606; UniProt:Q9UI12)

          * For research use only

      • Applications
        • Application
          WB; IHC (paraffin); ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:100-1:300
          ELISA 1:20000

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