Name: Anti-Ub antibody
Price: 224.00 USD

Overview
- Ub is a protein encoded by the UBA52 gene which is approximately 14, 7 kDa. Ub is localised to the cytoplasm and nucleus. It is involved in CDK-mediated phosphorylation and removal of Cdc6, RET signalling, activated TLR4 signalling, viral mRNA translation and the HIV life cycle. Ubiquitin exists either covalently attached to another protein, or free. When attached to a target protein, it has different functions depending on the Lys residue of the ubiquitin that is linked to. These functions including DNA repair and cell cycle regulation. Ub is expressed in the blood, nervous system, adrenal gland, muscle and liver. Mutations in the UBA52 gene may result in stomatitis. STJ97236 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Ub protein.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Synthesized peptide derived from human Ub.
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Ubiquitin-60S ribosomal protein L40; CEP52; Ubiquitin A-52 residue ribosomal protein fusion product 1; Ubiquitin; 60S ribosomal protein L40; Large ribosomal subunit protein eL40 (Gene ID:7311; UniProt:P0CG47)
  
  * For research use only