Name: Anti-TEK antibody
Price: 297.00 USD

Overview
- This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 500-750 of human TEK (NP_000450. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Angiopoietin-1 Receptor; Endothelial Tyrosine Kinase; Tunica Interna Endothelial Cell Kinase; Tyrosine Kinase With Ig And Egf Homology Domains-2; Tyrosine-Protein Kinase Receptor Tek; Tyrosine-Protein Kinase Receptor Tie-2; Htie2; P140 Tek; Cd Antigen Cd202b (Gene ID:7010; UniProt:Q02763)
  
  * For research use only