Name: Anti-Survivin antibody
Price: 224.00 USD

Overview
- Survivin is a protein encoded by the BIRC5 gene which is approximately 16, 3 kDa. Survivin is localised to the cytoplasm and nucleus. It is involved in apoptosis modulation and signalling, IL-23 signalling pathway and mitotic cell cycle. This protein falls under the inhibitor of apoptosis gene family. It is a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Survivin is expressed in the fetal kidney and liver, and to lesser extent, in the lung and brain. Mutations in the BIRC5 gene may result in ovarian epithelial cancer and cervical carcinosarcoma. STJ95838 was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous survivin protein.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Synthesized peptide derived from human Survivin around the non-phosphorylation site of T117.
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Baculoviral Iap Repeat-Containing Protein 5; Apoptosis Inhibitor 4; Apoptosis Inhibitor Survivin (Gene ID:332; UniProt:O15392)
  
  * For research use only