Name: Anti-SSRP1 antibody
Price: 297.00 USD

Overview
- The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SSRP1 (NP_003137. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Fact Complex Subunit Ssrp1; Chromatin-Specific Transcription Elongation Factor 80 Kda Subunit; Facilitates Chromatin Transcription Complex 80 Kda Subunit; Fact 80 Kda Subunit; Factp80; Facilitates Chromatin Transcription Complex Subunit Ssrp1; Recombination Signal Sequence Recognition Protein 1; Structure-Specific Recognition Protein 1; Hssrp1; T160 (Gene ID:6749; UniProt:Q08945)
  
  * For research use only