Anti-SHIP-1 antibody

Anti-SHIP-1 antibody

Catalog Number:
A001051025STJ
Mfr. No.:
STJ95655
Price:
$224
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      • Overview
        • SHIP-1 is a protein encoded by the INPP5D gene which is approximately 133, 3 kDa. SHIP-1 is localised to the cytoplasm and cell membrane. It is involved in inositol phosphate metabolism, RET signalling, B cell receptor signalling pathway and cell surface interactions at the vascular wall. This protein falls under the inositol polyphosphate-5-phosphatase family. It functions as a negative regulator of myeloid cell proliferation and survival. SHIP-1 is specifically expressed in immune and hematopoietic cells. Mutations in the INPP5D gene result in cancers of the immune system. STJ95655 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of SHIP-1 protein.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthesized peptide derived from human SHIP-1
          Purification
          The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
          Storage
          Store at -20°C and avoid repeat freeze-thaw cycles.
          Concentration
          1 mg/ml
          Regulatory Status
          RUO
          Antigen
          Phosphatidylinositol 3-4-5-Trisphosphate 5-Phosphatase 1; Inositol Polyphosphate-5-Phosphatase D; Inositol Polyphosphate-5-Phosphatase Of 145 Kda; Sip-145; Phosphatidylinositol 4-5-Bisphosphate 5-Phosphatase; Sh2 Domain-Containing Inositol 5'-Phosphatase 1; Sh2 Domain-Containing Inositol Phosphatase 1; Ship-1; P150ship; Hp51cn (Gene ID:3635; UniProt:Q92835)

          * For research use only

      • Applications
        • Application
          WB; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          ELISA 1:40000

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