Anti-RGS10 antibody

Anti-RGS10 antibody

Catalog Number:
A001019755STJ
Mfr. No.:
STJ111989
Price:
$297
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      • Overview
        • Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; rat
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human RGS10 (NP_001005339. 1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Regulator Of G-Protein Signaling 10; Rgs10 (Gene ID:6001; UniProt:O43665)

          * For research use only

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:200-1:500

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