Name: Anti-RelB antibody
Price: 224.00 USD

Overview
- RelB is a protein encoded by the RELB gene which is approximately 62, 1 kDa. RelB is localised to the nucleus and cytoplasm. It is involved toll-like receptor signalling pathways, NFAT in immune response, CDK-mediated phosphorylation and removal of Cdc6 and bacterial infections in CF airways. RelB makes up NF-kappa-B along with other Rel-like domain-containing proteins. It binds at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. RelB is expressed in the blood, lymph node, spleen and bone marrow. Mutations in the RELB gene result in reticuloendotheliosis. STJ95410 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of RelB protein.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Synthesized peptide derived from human RelB around the non-phosphorylation site of S552.
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Transcription Factor Relb; I-Rel (Gene ID:5971; UniProt:Q01201)
  
  * For research use only