Anti-Rat CD8a Monoclonal Antibody ( APC Conjugated ) (0.2 mg/mL) for Flow Cytometry

Anti-Rat CD8a Monoclonal Antibody ( APC Conjugated ) (0.2 mg/mL) for Flow Cytometry

Catalog Number:
A001087023RED
Mfr. No.:
RD21167F
Price:
$251
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1 kappa
          Reactivity
          rat
          Conjugate
          APC
          Formulation
          PBS with 0.05% Proclin300, 1% BSA
          Storage
          Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
          Concentration
          0.2 mg/mL
          Antigen
          T-cell surface glycoprotein CD8 alpha chain; CD8A; T-lymphocyte differentiation antigen T8/Leu-2; MAL (Gene ID:24930; UniProt:P07725)

          * For research use only.

      • Applications
        • Application
          Flow Cytometry

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