Anti-PTP4A2 antibody

Anti-PTP4A2 antibody

Catalog Number:
A001024373STJ
Mfr. No.:
STJ117530
Price:
$297
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      • Overview
        • The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human PTP4A2 (NP_536316. 1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Protein Tyrosine Phosphatase Type Iva 2; Hu-Pp-1; Ov-1; Ptp(CaaxII; Protein-Tyrosine Phosphatase 4a2; Protein-Tyrosine Phosphatase Of Regenerating Liver 2; Prl-2 (Gene ID:8073; UniProt:Q12974)

          * For research use only

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:200-1:2000

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