Anti-PRKAA1 antibody

Catalog Number:

A001034763STJ

Mfr. No.:

STJ25112

Price:

$297

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Overview
- The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PRKAA1 (NP_006242. 5).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  5'-Amp-Activated Protein Kinase Catalytic Subunit Alpha-1; Ampk Subunit Alpha-1; Acetyl-Coa Carboxylase Kinase; Acaca Kinase; Hydroxymethylglutaryl-Coa Reductase Kinase; Hmgcr Kinase; Tau-Protein Kinase Prkaa1 (Gene ID:5562; UniProt:Q13131)
  
  * For research use only