Name: Anti-PIAS2 antibody
Price: 297.00 USD

Overview
- This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 483-572 of human PIAS2 (NP_775298. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  E3 Sumo-Protein Ligase Pias2; Androgen Receptor-Interacting Protein 3; Arip3; Dab2-Interacting Protein; Dip; E3 Sumo-Protein Transferase Pias2; Msx-Interacting Zinc Finger Protein; Miz1; Pias-Ny Protein; Protein Inhibitor Of Activated Stat X; Protein Inhibitor Of Activated Stat2 (Gene ID:9063; UniProt:O75928)
  
  * For research use only