Anti-Phospho-CaMKI Beta/gamma/delta (T287) antibody

Anti-Phospho-CaMKI Beta/gamma/delta (T287) antibody

Catalog Number:
A001046313STJ
Mfr. No.:
STJ90941
Price:
$224
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      • Overview
        • CaMKII beta/gamma/delta is a protein encoded by the CAMK2B gene which is approximately 72, 6 kDa. CaMKII beta/gamma/delta is localised to the cytoplasm. It is involved in RET signalling, post NMDA receptor activation events and cardiac conduction. It is a calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation. It plays a role in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. CaMKII beta/gamma/delta is widely expressed in human tissue including the adult and foetal brain. The CAMK2B gene is associated with Phencyclidine abuse. STJ90941 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous CaMKII beta/gamma/delta protein which only binds about T287 when T287 is phosphorylated.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthesized peptide derived from human CaMKIIbeta/gamma/delta around the phosphorylation site of T287.
          Purification
          The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
          Storage
          Store at -20°C and avoid repeat freeze-thaw cycles.
          Concentration
          1 mg/ml
          Regulatory Status
          RUO
          Antigen
          Calcium/Calmodulin-Dependent Protein Kinase Type II Subunit Beta; Cam Kinase II Subunit Beta; Camk-II Subunit Beta (Gene ID:816; UniProt:Q13554)

          * For research use only

      • Applications
        • Application
          IF; WB; IHC (paraffin); ELISA
        • Application Dilutions
          IF 1:50-200
          WB 1:500-1:2000
          IHC 1:100-1:300
          ELISA 1:5000

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