Anti-PHKG2 antibody

Anti-PHKG2 antibody

Catalog Number:
A001022852STJ
Mfr. No.:
STJ115975
Price:
$297
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      • Overview
        • Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 237-406 of human PHKG2 (NP_000285. 1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Phosphorylase B Kinase Gamma Catalytic Chain-Liver/Testis Isoform; Phk-Gamma-Lt; Phk-Gamma-T; Psk-C3; Phosphorylase Kinase Subunit Gamma-2 (Gene ID:5261; UniProt:P15735)

          * For research use only

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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