Name: Anti-PDZK1 antibody
Price: 297.00 USD

Overview
- This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDZK1 (NP_001188254. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Na(+/H(+ Exchange Regulatory Cofactor Nhe-Rf3; Nherf-3; Cftr-Associated Protein Of 70 Kda; Na(+/H(+ Exchanger Regulatory Factor 3; Na/Pi Cotransporter C-Terminal-Associated Protein 1; Napi-Cap1; Pdz Domain-Containing Protein 1; Sodium-Hydrogen Exchanger Regulatory Factor 3 (Gene ID:5174; UniProt:Q5T2W1)
  
  * For research use only