Anti-PD2R antibody

Anti-PD2R antibody

Catalog Number:
A001050359STJ
Mfr. No.:
STJ94989
Price:
$224
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      • Overview
        • PD2R is a protein encoded by the PTGDR gene which is approximately 40, 2 kDa. PD2R is localised to the cell membrane. It is involved in peptide ligand-binding receptor, signalling by GPCR, celecoxib pathway and ibuprofen pathway. It is a receptor for prostaglandin D2. This receptor is mainly mediated by G proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. PD2R is expressed in ciliary epithelium, ciliary muscles, small intestine and platelet membranes. Mutations in the PTGDR gene may result in asthma. STJ94989 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PD2R protein.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Synthesized peptide derived from human PD2R
          Purification
          The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
          Storage
          Store at -20°C and avoid repeat freeze-thaw cycles.
          Concentration
          1 mg/ml
          Regulatory Status
          RUO
          Antigen
          Prostaglandin D2 Receptor; Pgd Receptor; Pgd2 Receptor; Prostanoid Dp Receptor (Gene ID:5729; UniProt:Q13258)

          * For research use only

      • Applications
        • Application
          WB; IHC (paraffin); IF; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:100-1:300
          IF 1:200-1:1000
          ELISA 1:5000

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