Anti-OTX2 antibody

Anti-OTX2 antibody

Catalog Number:
A001022848STJ
Mfr. No.:
STJ115971
Price:
$297
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      • Overview
        • This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 140-280 of human OTX2 (NP_068374. 1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Homeobox Protein Otx2; Orthodenticle Homolog 2 (Gene ID:5015; UniProt:P32243)

          * For research use only

      • Applications
        • Application
          WB; IHC
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:50-1:200

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