Name: Anti-MYOC antibody
Price: 297.00 USD

Overview
- MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 245-504 of human MYOC (NP_000252. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Myocilin; Myocilin 55 Kda Subunit; Trabecular Meshwork-Induced Glucocorticoid Response Protein Cleaved Into-Myocilin-N-Terminal Fragment; Myocilin 20 Kda N-Terminal Fragment-Myocilin-C-Terminal Fragment; Myocilin 35 Kda N-Terminal Fragment (Gene ID:4653; UniProt:Q99972)
  
  * For research use only