Anti-Mouse TCR V gamma 2 In Vivo Antibody - Ultra Low Endotoxin (UC3-10A6)

Anti-Mouse TCR V gamma 2 In Vivo Antibody - Ultra Low Endotoxin (UC3-10A6)

Catalog Number:
A001437648ICH
Mfr. No.:
ICH1140UL
Price:
$832
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      • Overview
        • Antigen Distribution: V gamma 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of gamma delta TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung.
          Isotype Control: Armenian Hamster IgG Isotype Control for In Vivo - Ultra Low Endotoxin [PIP] (ICH2251UL)
          Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method
          Aggregation: Aggregation level ≤ 1%

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          Background

          The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an alpha and beta chain in 95% of T cells, while 5% of T cells have TCRs consisting of gamma and delta chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.

      • Properties
        • Host
          armenian hamster
          Isotype
          IgG
          Reactivity
          mouse
          Clone
          UC3-10A6
          Purification
          >98% by SDS-PAGE and HPLC
          Formulation
          0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
          Storage
          anti-TCR V gamma 2 In Vivo Antibody - Ultra Low Endotoxin (UC3-10A6) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
          Molecular Weight
          ≥ 2.0 mg/ml
          Regulatory Status
          Each investigator should determine their own optimal working dilution for specific applications.
          Antigen
          (Gene ID:V gamma 2)

          * Products are for research use only. Not for use in diagnostic or therapeutic procedures.

      • Applications
        • Application
          Immunoprecipitation; WB

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