Name: Anti-Mouse NK1.1 In Vivo Antibody - Ultra Low Endotoxin (PK136)
Price: 832.00 USD

- Overview
  - Antigen Distribution: Mouse NK cells. Endogenous and interferon induced NK cells. Not present on cytotoxic T-cells and Con A stimulated blast cells. May be present on a certain subset of cytotoxic T-cells strains A, AKR, BALB/C, BALB.H-2b, CBA, C3H, DBA/2, 124 were negative using PK136.
    Specificity: Anti-NK1.1 In Vivo Antibody - Ultra Low Endotoxin (PK136) recognizes an epitope on Mouse NK1.1
    Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
    Isotype Control: Mouse IgG2a In Vivo Isotype Control - Ultra Low Endotoxin [C1.18.4] (ICH2245UL)
    Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method
    Aggregation: Aggregation level ≤ 1%
    
    Please contact us at for specific academic pricing.
    
    Background
    
    NK-1.1 surface antigen, also known as CD161b/CD161c, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
- Properties
  - Host
    
    mouse
    
    Isotype
    
    IgG2a kappa
    
    Reactivity
    
    mouse
    
    Clone
    
    PK136
    
    Immunogen
    
    NK-1+ cells from mouse spleen and bone marrow
    
    Purification
    
    >98% by SDS-PAGE and HPLC
    
    Formulation
    
    0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
    
    Storage
    
    anti-NK1.1 In Vivo Antibody - Ultra Low Endotoxin (PK136) is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
    
    Molecular Weight
    
    ≥ 2.0 mg/ml
    
    Regulatory Status
    
    Flow Cytometry: For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume.
    Each investigator should determine their own optimal working dilution for specific applications.
    
    Antigen
    
    (Gene ID:Natural Killer Cells, KR-P1C, NKR-P1B, Ly-55, CD161b, CD161c)
    
    * Products are for research use only. Not for use in diagnostic or therapeutic procedures.
- Applications
  - Application
    
    Immunoprecipitation; WB; Blocking; Flow Cytometry; CyTOF; IHC (frozen)

Anti-Mouse NK1.1 In Vivo Antibody - Ultra Low Endotoxin (PK136)

Anti-Mouse NK1.1 In Vivo Antibody - Ultra Low Endotoxin (PK136)

Background

We Also Recommend

Anti-Mouse Ly6G/Ly6C In Vivo Antibody - Ultra Low Endotoxin (RB6-8C5)

Anti-Mouse PD-1 (RMP1-14) - 5mg/ml . Low Endotoxin

Anti-Mouse, Human CD45R In Vivo Antibody - Ultra Low Endotoxin (RA3-6B2)