Anti-Mouse Ly6A/E ( Sca-1 ) Monoclonal Antibody ( AF647 Conjugated ) (0.5 mg/mL) for Flow Cytometry

Anti-Mouse Ly6A/E ( Sca-1 ) Monoclonal Antibody ( AF647 Conjugated ) (0.5 mg/mL) for Flow Cytometry

Catalog Number:
A001087859RED
Mfr. No.:
RD22111F
Price:
$268
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      • Overview
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          Background

          Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

      • Properties
        • Host
          rat
          Antibody Type
          monoclonal
          Isotype
          IgG2a kappa
          Reactivity
          mouse
          Conjugate
          Alexa-fluor®-647
          Formulation
          PBS with 0.05% Proclin300, 1% BSA
          Storage
          Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
          Concentration
          0.5 mg/mL
          Antigen
          Ly6a; Ly6; Ly-6A.2/Ly-6E.1; SCA-1; TAP (Gene ID:110454; UniProt:P05533)

          * For research use only.

      • Applications
        • Application
          Flow Cytometry

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