Name: Anti-Mouse LAG-3 In Vivo Antibody - Low Endotoxin (C9B7W)
Price: 680.00 USD

- Overview
  - Antigen Distribution: T-cells and NK cells
    Specificity: Anti-LAG-3 In Vivo Antibody - Low Endotoxin (C9B7W) recognizes an epitope on Mouse LAG-3
    Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
    Isotype Control: Rat IgG1 Isotype Control for In Vivo - Low Endotoxin [GL113] (ICH2246)
    Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
    Aggregation: Aggregation level ≤ 5%
    
    Please contact us at for specific academic pricing.
    
    Background
    
    LAG-3, also known as CD223, is 70 kD type I transmembrane glycoprotein within the Ig superfamily. CD223, like CD4, binds MHC class II molecules, but with higher affinity than CD4. Clone C9B7W antibody has been reported to block the function of murine LAG-3 in vivo and in vitro.
- Properties
  - Host
    
    rat
    
    Isotype
    
    IgG1 kappa
    
    Reactivity
    
    mouse
    
    Clone
    
    C9B7W
    
    Immunogen
    
    Murine CD223-Ig fusion protein
    
    Purification
    
    >95% by SDS-PAGE and HPLC
    
    Formulation
    
    0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
    
    Storage
    
    anti-LAG-3 In Vivo Antibody - Low Endotoxin (C9B7W) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
    
    Molecular Weight
    
    1.0 - 5.0 mg/ml
    
    Regulatory Status
    
    Blocking: Clone C9B7W antibody blocks the function of murine LAG-3 in vivo.
    Each investigator should determine their own optimal working dilution for specific applications.
    
    Antigen
    
    (Gene ID:Lymphocyte activation gene 3 protein, Aida, CD223)
    
    * Products are for research use only. Not for use in diagnostic or therapeutic procedures.
- Applications
  - Application
    
    WB; Blocking; Flow Cytometry; Immunoprecipitation; ELISA

Anti-Mouse LAG-3 In Vivo Antibody - Low Endotoxin (C9B7W)

Anti-Mouse LAG-3 In Vivo Antibody - Low Endotoxin (C9B7W)

Background

We Also Recommend

Anti-Mouse CTLA-4 In Vivo Antibody - Low Endotoxin (9H10)

Anti-Mouse CTLA-4 In Vivo Antibody - Low Endotoxin (UC10-4F10-11)

Anti-Mouse ICOS In Vivo Antibody - Low Endotoxin (7E.17G9)