Anti-Mouse IFN beta In Vivo Antibody - Low Endotoxin (HDB-4A7)

Anti-Mouse IFN beta In Vivo Antibody - Low Endotoxin (HDB-4A7)

Catalog Number:
A001437270ICH
Mfr. No.:
ICH1110
Price:
$680
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      • Overview
        • Specificity: Anti-IFN beta In Vivo Antibody - Low Endotoxin (HDB-4A7) recognizes an epitope on Mouse IFN-beta and binds specifically to murine IFNbeta and does not bind murine IFNg or several different IFNa species (a-1,4,5 or 13); HDb-4A7 binds both recombinant and natural forms
          Purification method: This antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
          Isotype Control: Mouse IgG2a In Vivo Isotype Control - Low Endotoxin [C1.18.4] (ICH2245)
          Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
          Aggregation: Aggregation level ≤ 5%

          Please contact us at for specific academic pricing.

      • Properties
        • Host
          mouse
          Isotype
          IgG2a
          Reactivity
          mouse
          Clone
          HDB-4A7
          Immunogen
          Plasmid DNA encoding murine IFNb
          Purification
          >95% by SDS-PAGE and HPLC
          Formulation
          0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
          Storage
          anti-IFN beta In Vivo Antibody - Low Endotoxin (HDB-4A7) is stable when stored at 2-8°C. Do not freeze. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
          Molecular Weight
          1.0 - 5.0 mg/ml
          Regulatory Status
          Blocking: Blocks in vivo IFNb leading to increased the lethality of mice infected with West Nile Virus (WNV), similar to the susceptibility of IFNb-/- mice. Clone HDB-4A7 circulates with a half-life of ~ 14 days.
          Each investigator should determine their own optimal working dilution for specific applications.

          * Products are for research use only. Not for use in diagnostic or therapeutic procedures.

      • Applications
        • Application
          WB; Blocking; Functional Assays

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